動物氣溶膠給藥器

氣溶膠霧化器能夠產生穩(wěn)定、細膩的氣溶膠，給動物暴露實驗或者細胞暴露實驗提供穩(wěn)定的霧化環(huán)境。

氣溶膠霧化器是全身暴露或者口鼻暴露的重要組成部分，可配合暴露箱或者暴露塔使用，將藥物霧化后的氣溶膠推送到暴露內，并持續(xù)霧化和維持暴露箱內一定的氣溶膠濃度。

我們可以提供Aerogen Pro霧化器和Aerogen Solo霧化器：設備采用鈀合金振動網格技術，中心孔板直徑5mm，均勻分布著1000個精密成形微孔，每秒振動128,000次，形成非常有利于沉淀入肺部沉積的氣溶膠顆粒滴。

型號：Aerogen Pro

型號：Aerogen Solo

產品主要優(yōu)勢:

· 霧化劑量小；
· 粒度分布和顆粒物體濃度具有高度的可重復性；
· 隨時可填充藥物，也可以加配注射泵自動添加藥物；
· 抗腐蝕外殼設計，持久耐用；
· 高度集成化、體積小巧；
· 操作簡單，無需復雜的培訓工作；

·小型：Volume Median Diameter(VMD)
· 霧化速率：>0.1mL/min
· 顆粒尺寸：VMD （體積中值直徑）介于2.5μm and 4.0μm
· 藥物殘余量：<0.1mL 

· 液體霧化氣溶膠在科學研究、藥物開發(fā)、質量檢測中有很多應用；

霧化的顆粒物粒徑分布：

霧化的顆粒物粒徑分布：  

根據(jù)需要，您還可以選擇BGI Collison氣溶膠發(fā)生器

有多種規(guī)格和尺寸可供選擇，可以根據(jù)客戶的需求進行定制：
 

我們還可以根據(jù)實驗室需求，推薦更適合的霧化染毒搭配方案，敬請。

粉塵氣溶膠發(fā)生器，可對粉塵進行霧化，產生穩(wěn)定的粉塵氣溶膠

氣溶膠濃度測量儀，用于對暴露環(huán)境的氣溶膠濃度進行實時測量

動物暴露染毒箱，用于對動物進行長時間的氣溶膠暴露

氣溶膠發(fā)生器部分參考文獻：
1.Sidler-Moix A L, Di Paolo E R, Dolci U, et al. Physicochemical aspects and efficiency of albuterol nebulization: comparison of three aerosol types in an in vitro pediatric model[J]. Respiratory care, 2015, 60(1): 38-46.
2.Hassan A, Rabea H, Hussein R R S, et al. In-vitro characterization of the aerosolized dose during non-invasive automatic continuous positive airway pressure ventilation[J]. Pulmonary Therapy, 2016, 2: 115-126.
3.ElHansy M H E, Boules M E, El Essawy A F M, et al. Inhaled salbutamol dose delivered by jet nebulizer, vibrating mesh nebulizer and metered dose inhaler with spacer during invasive mechanical ventilation[J]. Pulmonary pharmacology & therapeutics, 2017, 45: 159-163.
4.Fang T P, Lin H L, Wan G H, et al. In vitro evaluation of aerosolized delivery of various medications during mechanical ventilation[J]. 2017.
5.Abdelrahim M E A, Saeed H, Harb H S, et al. The Aerosol Generators Available for Critically Ill Patient[J]. Essentials of Aerosol Therapy in Critically ill Patients, 2021: 115-135.
6.ElHansy M H E, Boules M E, El Essawy A F M, et al. Inhaled salbutamol dose delivered by jet nebulizer, vibrating mesh nebulizer and metered dose inhaler with spacer during invasive mechanical ventilation[J]. Pulmonary pharmacology & therapeutics, 2017, 45: 159-163.
7.Gowda A A, Cuccia A D, Smaldone G C. Reliability of vibrating mesh technology[J]. Respiratory Care, 2017, 62(1): 65-69.
8.Gerde P, Nowenwik M, Sj?berg C O, et al. Adapting the aerogen mesh nebulizer for dried aerosol exposures using the preciseinhale platform[J]. Journal of aerosol medicine and pulmonary drug delivery, 2020, 33(2): 116-126.
9.Michotte J B, Staderini E, Le Pennec D, et al. In vitro comparison of a vibrating mesh nebulizer operating in inspiratory synchronized and continuous nebulization modes during noninvasive ventilation[J]. Journal of aerosol medicine and pulmonary drug delivery, 2016, 29(4): 328-336.
10.Cahill R A, Dalli J, Khan M, et al. Solving the problems of gas leakage at laparoscopy[J]. British Journal of Surgery, 2020, 107(11): 1401-1405.
11.Sarhan R M, Elberry A A, Abdelwahab N S, et al. Effect of a nebulizer holding chamber on aerosol delivery[J]. Respiratory care, 2018, 63(9): 1125-1131.